NL-OMON55153已完成不适用
The influence of CYP2C19 loss-of-function alleles on atherothrombotic events in patients on clopidogrel after endovascular aneurysm repair (EVAR) - GEN-EVAR
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- adult patients (age > 18 years)
- •- obtained written informed consent
- •- patients with the ability to perform a buccal swab at home
- •- patients who were treated for an infrarenal AAA with EVAR between January
- •2016 and July 2019, including those that were additionally treated with an
- •iliac branched device and/or coiling of the internal iliac artery
- •- patients who are on continues treatment with clopidogrel as single
- •thrombocyte aggregation inhibitor since EVAR
排除标准
- •- patients with a known CYP2C19*2 and *3 status
- •- patients who are treated with other antithrombotic medications (aspirin,
- •ticagrelor, prasugrel, coumarins, Non-vitamin K Oral Anti-Coagulants (NOACs),
- •in combination with clopidogrel
- •- Patient treated for a juxtarenal AAA with Fenestrated-EVAR, Chimney-EVAR or
- •open surgical repair
- •- Patients that have used clopidogral only temporary after EVAR
研究者
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