NL-OMON29281尚未招募不适用
The influence of CYP2C19 loss-of-function alleles on atherothrombotic events in patients on clopidogrel after endovascular aneurysm repair (EVAR)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 300
研究概览
简要总结
ot applicable
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •Adult patients (age 18 years)
- •- Obtained written informed consent
- •- Patients with the ability to perform a buccal swab at home
- •- Patients who underwent EVAR for an infrarenal AAA between January 2016 and April 2020, including those that were additionally treated with an iliac branched device and/or coiling of the internal iliac artery
- •- Patients who are on continues treatment with clopidogrel as single antiplatelet therapy since EVAR
排除标准
- •- Patients with a known CYP2C19 genotype or metabolizer state
- •- Patients who are treated with other anticoagulants such as aspirin, ticagrelor, prasugrel, coumarins or Non vitamin K Oral Anti-Coagulants (NOACs)
- •- Patient treated for a juxtarenal AAA with Fenestrated EVAR, Chimney EVAR or open surgical repair
- •- Patients that have used clopidogrel only temporary after EVAR
研究者
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