Effects of Xanthophylls on Optical Density

Not Applicable

Completed

• Conditions: Age-Related Macular Degeneration
• Interventions: Dietary Supplement: Verum; Dietary Supplement: Placebo

• Registration Number: NCT01316198
• Lead Sponsor: University of Jena

Brief Summary

The objective of the study was to investigate the influence of a intervention with lutein und zeaxanthin from crucifers on the optical density of the macular pigment of patients with non exudative age-related maculopathy. It is hypothesized that the applied study beverage elevates plasma concentrations of the administered xanthophylls and the optical density after 4 weeks of intervention.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2011-03-15
• Study First Submitted QC: 2011-03-15
• Study First Posted: 2011-03-16
• Primary Completion: 2011-06
• Study Completion: 2011-07
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-26
• Last Update Posted: 2012-07-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• patients with non exudative age-related maculopathy

Exclusion Criteria

• intake of dietary supplements containing lutein and zeaxanthin

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lutein and zeaxanthin	Verum	-
Placebo	Placebo	-

Primary Outcome Measures

Name	Time	Method
Optical density of macular pigment in AMD patients	10 weeks

Secondary Outcome Measures

Name	Time	Method
Concentration of xanthophylls in plasma of AMD patients	10 weeks
blood lipids	10 weeks

Trial Locations

Locations (1)

Friedrich Schiller University; 🇩🇪 Jena, Thuringia, Germany