Prospective observational study to determine aetiologies, presentation, clinical practice patterns and outcomes of hypertension in high risk hypertensive patients in India

Dr Reddys Laboratories Ltd0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1.Patient willing to give informed consent.
•2.Patients both males and females 18 years or older with essential hypertension (As per ESC/ESH 2018 and IGH 2019 guidelines) for at least 4 weeks, following up in public and private centres and after signing a consent form.
•3.Patients defined as high-risk and very high-risk hypertensive as per ESC/ESH 2018 [17] and IGH 2019 guidelines [11] as per the check-list below:
•a.Grade 3 hypertension (SBP >=180 mm Hg OR DBP >=110 mm Hg) with any one of the following:
•i.No risk, 1-2 risk factor or >=3 cardiovascular risk factors
•ii.Asymptomatic HMOD (hypertension-mediated organ damage)
•iii.CKD grade 3 (eGFR >30 to 59 ml/min/1.73m2), or grade 4 (eGFR <30 ml/min/1.73m2)
•iv.Diabetes mellitus without/with organ damage
•v.Established CVD
•b.Grade 2 hypertension (SBP 160-179 mm Hg OR DBP 100-109 mm Hg) with any one of the following:
•i.Uncomplicated hypertension with >=3 cardiovascular risk factors
•ii.Asymptomatic HMOD (hypertension-mediated organ damage)
•iii.CKD grade 3 (eGFR >30 to 59 ml/min/1.73m2), or grade 4 (eGFR <30 ml/min/1.73m2)
•iv.Diabetes mellitus without/with organ damage
•v.Established CVD
•c.Grade 1 hypertension (SBP 140-159 mm Hg OR DBP 90-99 mm Hg) with any one of the following:
•i.Asymptomatic HMOD (hypertension-mediated organ damage)
•ii.CKD grade 3 (eGFR >30 to 59 ml/min/1.73m2), or grade 4 (eGFR <30 ml/min/1.73m2)
•iii.Diabetes mellitus without/with organ damage
•iv.Established CVD

•1.Patients with secondary hypertension (secondary hypertension is the hypertension caused by an identifiable underlying primary cause).
•2.Pregnant and lactating women.
•3.Patient refusing consent for enrolment.
•4.Any patient as per the discretion of the physician.

发起方