Salivary Cortisol in Intensive Care Unit
- Conditions
- Critically Ill
- Interventions
- Other: Salivary cortisol test
- Registration Number
- NCT02001207
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
In critical illness, patients are highly stressed and should have elevated cortisol (stress hormone) secretion to adapt to stress. Dysfunction of this system is referred to as critical illness-related corticosteroid insufficiency. Free cortisol (unbound form) which is mainly responsible for its physiologic function is difficult to measure. We hypothesized that the salivary cortisol, which can be obtained by noninvasive methods, can more accurately evaluate adrenal function of critically ill patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- patients who agreed to participate
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Exclusion Criteria
- Known adrenal or pituitary disease
- oral bleeding
- currently on systemic or inhaled corticosteroids
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description MICU patients Salivary cortisol test -
- Primary Outcome Measures
Name Time Method Overall mortality 28 days
- Secondary Outcome Measures
Name Time Method ICU days 28 days ventilator-free days 28 days
Trial Locations
- Locations (1)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of