De relatie tussen geslacht, lichaamssamenstelling en het succesvol kunnen verminderen van medicijnen (TNF blokkers) bij patiënten met de ziekte van Bechterew.
Recruiting
- Conditions
- ankylosing spondylitis, Bechterew, TNF blocker, spondylitis ankylopoetica, spondyloarthritis, TNF blokker
- Registration Number
- NL-OMON21138
- Lead Sponsor
- VU university medical center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 190
Inclusion Criteria
• 18 years or older
• AS (radiographic axial spondyloarthritis) according to the 1984 modified New York Criteria
Exclusion Criteria
• Planned reasons for treatment discontinuation (e.g. pregnancy)
• Unable to understand the study aims and methods
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the presence of an AS disease flare (ASDAS of 2.1 or higher during at least 2 weeks).
- Secondary Outcome Measures
Name Time Method - parameters of body composition: <br />anthropometrical measurements and DEXA parameters (e.g. body fatt, lean mass)<br /><br>- other parameters of AS disease activity (BASDAI, VAS, BASFI, BASMI, 44 joint count, quality of life)<br /><br>- the presence of extra articular manifestations<br /><br>- cardiovascular risk factors<br /><br>- through levels of TNF inhibitor<br />