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临床试验/CTRI/2022/12/048314
CTRI/2022/12/048314尚未招募不适用

Confirmation of endotracheal tube placement during general anaesthesia by ultrasonography.

Dr Harshitha K1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2022年12月22日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
160
试验地点
1
主要终点
TO MEASURE THE TIME REQUIRED BY TANSTRACHEAL ULTRASONOGRAPHY TO CONFIRM THE ENDOTRACHEAL TUBE PLACEMENT.

研究概览

简要总结

The cornerstone of airway management and resuscitation of patients is ‘rapid and accurate endotracheal tube placement’. Securing a definitive airway in any setting as in operation theatre, intensive care unit (ICU), emergency department is always a necessary.

Various methodologies like visualization of vocal cords during laryngoscopy followed by endotracheal tube placement, chest wall expansion following ventilation, visualization of tracheal rings and carina by bronchoscopy, chest auscultation, capnometry or capnography are available for confirmation of endotracheal tube placement. But there is no perfect modality for confirmation and very few methods are reliable.  Constant non-availability of these modalities is a major drawback.

The Advanced Cardiac Life Support (ACLS) 2015 guidelines recommend the usage of capnographic waveform along with clinical assessment for confirmation of endotracheal tube placement. Capnography is said to be the gold standard for confirmation which works on the principle of carbon dioxide detection, but has its own limitations like the availability in emergency departments and its dependency on adequacy of pulmonary blood flow makes it non reliable in conditions like pulmonary embolism, low cardiac output states, cardiac arrest (where cardiopulmonary resuscitation is not initiated/arrest for a prolonged period) and airway obstruction. False results have been noted when epinephrine was used.

Ultrasonography is now emerging as a promising tool for rapid assessment of endotracheal tube placement. Ultrasound machine is portable, widely available, non-invasive, cost effective, easy reproducibility of images and has good safety record. Moreover, its available in all settings like emergency department, ICU and operation theatre. Confirmation of endotracheal tube in the trachea is confirmed by absence of “ Snow storm sign†(disturbance of tracheal air-mucosa interface with comet tail artefacts) visualized in ultrasound. Learning curve of transtracheal ultrasound has also been observed to be not difficult. Hence it can be used as a potential alternative to capnography during non-availability or when there is compromise in carbon dioxide detection by capnography.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • 1.ALL PATIENTS POSTED FOR ELECTIVE SURGERY UNDER GENERAL ANAESTHESIA WITH ORO TRACHEAL INTUBATION. 2.PATIENTS BELONGING TO ASA.
  • PS I AND II.

排除标准

  • 1.PATIENTS WITH KNOWN PREDICTORS OF DIFFICULT INTUBATION.
  • BMI MORE THAN 30KG/M
  • PREVIOUS HISTORY OF DIFFICULT INTUBATION.

结局指标

主要结局

TO MEASURE THE TIME REQUIRED BY TANSTRACHEAL ULTRASONOGRAPHY TO CONFIRM THE ENDOTRACHEAL TUBE PLACEMENT.

时间窗: FROM THE TIME OF LARYNGOSCOPY TILL THE TIME OF APPEARANCE OF BULLET SIGN ON ULTRASONOGRAPHY.

次要结局

  • DETERMINE THE RELIABILITY OF TRANSTRACHEAL ULTRASONOGRAPHY TO DETECT THE CORRECT PLACEMENT OF ENDOTRACHEAL TUBE.(TO DETERMINE THE RELIABILITY OF TRANSTRACHEAL ULTRASONOGRAPHY TO DETECT THE CORRECT PLACEMENT OF ENDOTRACHEAL TUBE.)

研究者

发起方
Dr Harshitha K
申办方类型
Other []

研究点 (1)

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