Rosuvastatin augments dipyridamole induced vasodilation by increased adenosine receptor stimulatio

• Conditions: Ischemia-reperfusion injury; MedDRA version: 9.1Level: LLTClassification code 10023034Term: Ischemia peripheral

• Registration Number: EUCTR2007-004762-40-NL
• Lead Sponsor: Dept. Pharmacology and Toxicology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08-29
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Age between 18 and 50 years
Signed infomed consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Hypertension (systole > 140 mmHg, diastole > 90 mmHg)
Hypercholesterolemia (fasting total cholesterol > 6.0 mmol/l)
Diabetes mellitus (fasting glucose > 7.0 mmol/l, random glucose > 11.0 mmol/l)
Alanine amino transferase > 90 U/l (twice the upper level of normal range)
Creatinine Kinase > 440 U/l (twice the upper level of normal range)
Cardiovascular disease
Participation in any clinical trial in the last 60 days
Concomitant medication use

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified