Brain Network Mechanisms Causally Underlying Human Decisions Revealed by Brain Stimulation and Functional MRI

Christian Ruff0 sites1,800 target enrollmentSeptember 1, 2021

ConditionsBehavior and Behavior Mechanisms

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Behavior and Behavior Mechanisms
Sponsor: Christian Ruff
Enrollment: 1800
Primary Endpoint: Cognitive Function driving Behaviour
Status: Not yet recruiting
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

We will examine how stimulation of specific brain areas with transcranial magnetic stimulation (TMS) or transcranial electric stimulation (tES) changes specific aspects of behavior and brain activity, in order to test hypotheses about brain behavior relationships (basic research).

Registry

clinicaltrials.gov

Start Date

September 1, 2021

End Date

September 30, 2025

Last Updated

4 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Christian Ruff

Responsible Party

Sponsor Investigator

Principal Investigator

Christian Ruff

Prof. Dr.

University of Zurich

Eligibility Criteria

Inclusion Criteria

•between 18 and 80 years of age (whereby for most studies the majority of recruited participants will be between 18 and 40 years of age)
•right-handedness and/or one specific gender (male or female) can be inclusion criteria to reduce variation in the data.

Exclusion Criteria

•inability to understand the instructions and insufficient knowledge of the project language
•Internal electronic and/or metallic objects in the head, neck, or shoulders (e.g. artificial cochleae, deep brain stimulators, medical pumps, shrapnel, metallic splinters due to accidents during metal welding)
•One or more epileptic fits in the participant or a first-degree relative
•Vascular, traumatic, tumoral, infectious, or metabolic brain damage
•Use of medication that significantly alters cortical excitability
•Acute sleep deprivation or withdrawal from alcohol
•pregnancy
•to reduce bias, students of psychology or economics can be excluded if there is a possibility that they are familiar with the relevant paradigm.