Comparison of Dexamethasone 4 mg and 8 mg as an Adjuvant to 0.5% Bupivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgeries
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare duration and onset of sensory and motor blockage in both group
研究概览
简要总结
Brachial plexus block has evolved as an important tool as a safe alternative to general anaesthesia for upper limb surgery and peri-operative analgesia.Bupivacaine is a potent local anaesthetic drug widely used for prolonged local and regional anaesthesia.Many additives can be added to local anaesthetics such as opioids, clonidine, tramadol, dexmedetomidine, dexamethasone that have been used to increase the duration of the block, to improve the postoperative pain management.In this study we compare duration of analgesia, onset and duration of sensory and motor block and hemodynamic parameters in supraclavicular brachial plexus block with Dexamethasone 4mg and 8mg as an adjuvant to 0.5% Bupivacaine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade : I,II,III
- •Elective upper limb surgeries under supraclavicular brachial plexus block.
- •Patient giving consent.
排除标准
- •Any bleeding disorder and patient on anticoagulants
- •Contralateral lung injury and rib fracture
- •Pre-existing neuropathy involving the surgical limb
- •Local infection at the injection site
- •History of allergy to local anaesthetic and dexamethasone
- •Patients with a history of peptic ulcer disease, hepatic or renal failure (contraindication to steroids)
- •Pregnant women
- •Systemic use of corticosteroids for 2 weeks or longer within 6 months of surgery
- •Unwilling patient.
结局指标
主要结局
To compare duration and onset of sensory and motor blockage in both group
时间窗: To compare duration and onset of sensory and motor blockage in both group starting from baseline to every 3 min with 3 point scale method.
次要结局
- To compare hemodynamic parameter intraoperative and To compare complication intraoperative and postoperative in both group(24 hour postoperative)
研究者
Dr Jigneshkumar chauhan
B.J. Medical College and Civil Hospital , Ahmedabad