A clinical trial to look for benefits of delayed cord clamping against immediate cord clamping in resuscitation of preterm neonates.
Not Applicable
- Conditions
- Health Condition 1: P84- Other problems with newborn
- Registration Number
- CTRI/2024/02/062956
- Lead Sponsor
- ABVIMS and Dr RML Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Preterm neonate <34 wk gestation are eligible
2. Parental informed consent obtained.
3. Gender – both
Exclusion Criteria
1. Known severe congenital/chromosomal abnormality
2. Twin-to-twin transfusion syndrome
3. Twin anemia polycythemia syndrome
4. Monochorionic twins
5. Rh sensitization
6. Hydrops
7. Retropositive mother
8. Abruptio placentae, Total placenta praevia
9. Precipitate labor
10.Invasive placentations [increta, percreta]
11.Multifetal pregnancy
12.Refusal to consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the impact of initiating resuscitation with an intact cord vs immediate cord clamping on the need of positive pressure ventilation among non vigorous preterm neonates (34 weeks).Timepoint: 1 minute of life
- Secondary Outcome Measures
Name Time Method 1. Cerebral blood flow changes <br/ ><br>2. Apgar at 1 & 5 Minute <br/ ><br>3. Time to spontaneous breathing (Seconds) <br/ ><br>4. Temperature at 15 Minutes Of Life <br/ ><br>5. Admission Temperature (C) <br/ ><br>6. Need of inotropes in the first 24 hours <br/ ><br>7. IVH grade 2 or more <br/ ><br>8. Mortality within the first week of lifeTimepoint: 1. 24 hours of life <br/ ><br>2. 1 & 5 Minute of life <br/ ><br>3. 5 minute of life <br/ ><br>4. 15 Minutes Of Life <br/ ><br>5. Time of admission <br/ ><br>6. 24 hours of life <br/ ><br>7. Day 1,3,7,14 of life <br/ ><br>8. Day 7 of life