Efficacy of early fluid resuscitation combined with Chaiqin Chengqi Decoction in treatment of acute pancreatitis: a randomized controlled trial.
Phase 1
- Conditions
- acute pancreatitis
- Registration Number
- ITMCTR2000003450
- Lead Sponsor
- West China Hospitial, Sichuan University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Aged 18-75 years;
2. Meet the diagnostic criteria for AP;
3. Admitted to the Department of Integrated Traditional Chinese and Western Medicine within 72 hours from the onset.
Exclusion Criteria
1. Pregnant or lactating women;
2. severe organ dysfunction;
3. HAPS score > 2;
4. Combined with any malignant tumor or history of chemoradiotherapy within 6 months;
5. perforation or bleeding of digestive tract, or intestinal obstruction, etc. which is not suitable for CQCQD administration orally or by enema;
6. acute attack of chronic pancreatitis;
7. any tumor of duodenal, billiary, pancreatic system;
8. history of pancreatectomy;
9. iatrogenic pancreatitis or being received other treatment which potentially interferes the study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cumulative CRP;Duration of respiratory failure;
- Secondary Outcome Measures
Name Time Method classification of RAC;Local pancreatic injury;operation rate;use of ventilator;duration of SIRS;(Peri)pancreatic infection;Useage of CRRT;pancreatic exocrine function;clinical scoring system;length of stay;mortality;life quality scale;length of stay in ICU;Consumption of analgesics;PASS score;