Randomized Controlled Research of Revascularization in Immature Permanent Teeth With Periapical Periodontitis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 190
- 试验地点
- 1
- 主要终点
- Evidence of lesion healing confirmed by cone beam computed tomography
研究概览
简要总结
Revascularization is an alternative new treatment of immature permanent teeth with necrotic pulp nowadays while apexification is the traditional therapy. The investigators suppose that revascularization is superior to apexification at developing the root of immature permanent teeth and reducing the risk of root fracture,and the research is designed.
详细描述
The investigators design to collect a group of patients presenting immature permanent teeth with periapical periodontitis in certain criterion. The investigators will divide the patients into two groups randomly. One group will get treated with revascularization while the other with apexification. The investigators want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of revascularization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •clinical diagnosis of periapical periodontitis
- •must be immature permanent teeth
- •must be local Guangzhou
排除标准
- •blood disease
- •residual root that is advised to extract
- •serious periodontitis
- •women in pregnancy
结局指标
主要结局
Evidence of lesion healing confirmed by cone beam computed tomography
时间窗: one year
次要结局
未报告次要终点
研究者
Junqi Ling
Dean, professor
Sun Yat-sen University