Efficacy of microcurrent electrical stimulation to improve symptoms of carpal tunnel syndrome and tissue stiffness improvement quantified by acoustic radiation force impulse(ARFI) elastography.

Not Applicable

Conditions: Diseases of the nervous system

Registration Number: KCT0002535

Lead Sponsor: Soon Chun Hyang University Hospital Seoul

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot yet recruiting

Sex: All

Target Recruitment: 36

Inclusion Criteria

1)+2), 1) At least one of those symptoms; tingling, dysesthesia, hypesthesia, pain on 1st-3rd fingers and/or palm; positive for Phalen and/or Tinel sign, 2) Diagnosed as carpal tunnel syndrome by electromyography and/or ultrasonography.

Exclusion Criteria

Participants were excluded if they (1) have history of diseases similar to symptoms of carpal tunnel syndrome, such as cervical radiculopathy, polyneuropathy, and ulnar or other entrapment neuropathies; (2) had surgical treatment for carpal tunnel syndrome; (3) had history of recent trauma or fracture on the wrist; (4) were diagnosed for ulnar entrapment by electromyography; (5) have anatomical variation without any definite ultrasonographic evaluation methods, such as bifid median nerves and aberrant persistent median artery; (6) Martin-Gruber anastomosis or other anatomic variations that median and ulnar nerves are fused; (7) had local corticosteroid injection therapy on the wrist in 6 months.

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Static ultrasound imaging: (1)CSA of median nerve at carpal tunnel inlet(pisiform bone – scaphoid tubercle), (2)? (Delta) CSA of median nerve = CSA at proximal third of pronator quadratus – maximal CSA within carpal tunnel, (3)CSA ratio ;Korean version of the Boston Carpal Tunnel Questionnaire (K-BCTQ)

Secondary Outcome Measures

Name	Time	Method
Shear-wave elastography - Site: at carpal tunnel inlet -> 2x2mm ROI(Region of interest), (1) Median nerve (1 site), (2) Flexor digitorum superficialis & profundus (1 site each), (3) Transverse carpal ligament (2 sites);??: Electromyography (1) Sensory nerve action potential: onset latency, amplitude, conduction velocity; (2) Compound motor action potential: distal latency, amplitude, conduction velocity; (3) Needle electromyography of affected side