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临床试验/NCT04970550
NCT04970550已完成不适用

Vaccination Against SARS-Cov2 in Chronic Inflammatory Rheumatism and Factors Determining Its Decision.

Hopital Nord Franche-Comte1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2021年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
150
试验地点
1
主要终点
Determine the desire to be vaccinated against SARS-CoV2

研究概览

简要总结

Rheumatoid arthritis and spondyloarthritis (ankylosing spondylitis and psoriatic arthritis mainly) are chronic inflammatory rheumatism (RIC), frequently onset in young adults. The prevalence is respectively 0.3 to 0.8% and 0.4%. or about 600,000 people. The "basic" treatments (DMARDs), essential to control the progression of the disease, are classified into csDMARDs (chemical), the first of which is methotrexate, or bDMARDs (biological). These treatments are immunomodulators and there is an increased risk of severe infection under these therapies. Several vaccinations are therefore recommended by learned societies in patients receiving these treatments, in order to prevent certain infectious risks.In the current pandemic context, the vaccination of these patients against SARS-Cov2 is a major issue in their management and is recommended by the French society of rheumatology. However, many patients express doubts about this vaccination or refuse it. The factors associated with the vaccination will are not known. Better identifying them would make it possible to adapt the information to be given to our patients to promote their adherence.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ambulatory patients
  • Men or women of any age
  • Follow-ups for chronic inflammatory rheumatism such as rheumatoid arthritis or spondyloarthritis
  • Treated with methotrexate or biotherapy.

排除标准

  • Patients not treated with biotherapy or methotrexate.
  • Patients in whom the assessment could not be performed reliably

结局指标

主要结局

Determine the desire to be vaccinated against SARS-CoV2

时间窗: At inclusion

Percentage of patients with RIC and treated with DMARDs who favor vaccination against SARS-CoV2 ; determined with a questionnaire

次要结局

  • Factors associated with the desire for vaccination against SARS-CoV2(At inclusion)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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