Long Term Outcomes of Patients With COVID-19
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 入组人数
- 500
- 试验地点
- 2
- 主要终点
- Quality of Life score
研究概览
简要总结
The investigators hypothesize that those with respiratory failure due to COVID-19 will have different burdens of mental and physical disability than those with respiratory failure who do not have COVID-19. Detecting these potential differences will lay an important foundation for treating long term sequelae of respiratory failure in these two cohorts.
详细描述
The aim of this proposal to is to understand the extent and degree of physical disability, psychological sequelae, and cognitive dysfunction survivors of COVID-19 related critical illness will have upon hospital discharge, 6 months, and up to one year post discharge. These outcomes of interest will be evaluated prospectively. The investigators will perform these measures in Covid-19 patients with respiratory failure and compare them to non-Covid-19 patients with respiratory failure. The investigators also seek to determine the risk factors of these long-term complications in order to guide providers as to which patients should be screened for these deficits. Finally, the investigators will examine the association of various critical care interventions such as invasive versus noninvasive mechanical ventilation or use of sedatives and their effects on disability and cognitive dysfunction.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients admitted to the ICU
排除标准
- 未提供
研究组 & 干预措施
COVID19 positive
ICU patients coronavirus positive
干预措施: Quality of Life (Other)
COVID19 positive
ICU patients coronavirus positive
干预措施: Impact Event Score (Other)
COVID19 positive
ICU patients coronavirus positive
干预措施: Hospital anxiety and depression scale (Other)
non-COVID19
ICU patients without coronavirus
干预措施: Quality of Life (Other)
结局指标
主要结局
Quality of Life score
时间窗: up to 12 months after discharge
SF-36 score
次要结局
- Psychological Sequelae(up to 12 months after discharge)
- cognitive dysfunction(up to 12 months after discharge)
- Functional Status Score(up to 12 months after discharge)
- Physical Disability(up to 12 months after discharge)
