TCTR20201229004招募中3 期
Intranasal ketamine versus intravenous morphine for older adults with musculoskeletal pain in the emergency department: a randomized controlled trial
navamindradhiraj research fund0 个研究点目标入组 100 人开始时间: 2020年12月29日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 65 Years 至 120 Years(—)
- 性别
- All
入选标准
- •1. Patient age more than 65 years presenting to the ED
- •2. Musculoskeletal pain within 7 days
- •3. Moderate to severe pain(Numeric rating scale 5-10)
排除标准
- •1. Lack of Informed consent
- •2. Hemodynamic instability ( SBP < 90 or > 180 mmHg, PR < 50 or > 150 bpms, RR < 10 or > 30 bpms)
- •3. History of acute head or eye injury
- •4. Seizure
- •5. Intracranial hypertension
- •6. Severe chronic obstructive pulmonary disease
- •7. Chronic pain
- •8. Psychological disorder
- •9. Immediate surgical intervention
- •10. Altered mental status
- •11. Alcohol and drug abuse
- •12. Nasopharyngeal deformity
- •13. Recent opioid use (4 hr before)
- •14. Ketamine and morphine allergy/addiction
- •15. Renal (CrCl <50) or hepatic insufficiency
- •16. Patients with a history of risk or exposure to COVID-19 disease according to the notification of the Department of Disease Control.
研究者
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