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临床试验/NCT07632430
NCT07632430进行中(未招募)不适用

End-Tidal CO2 (ETCO2) Trends in Out-of-Hospital Cardiac Arrest

Office of the Medical Director for EMS in Oklahoma City and Tulsa1 个研究点 分布在 1 个国家目标入组 3,500 人开始时间: 2024年1月1日最近更新:

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
3,500
试验地点
1

研究概览

简要总结

The investigators aim to assess the relationship between patient characteristics, prehospital treatments, and vital signs to determine if a threshold EtCO2 value, a change in EtCO2 value (final - initial), or a trend in EtCO2 (positive/negative) is a better predictor of patient survival to discharge. The secondary aim of this project is to identify significant predictors of neurologically intact patient survival as indicated by a cerebral performance category (CPC) score of 1-2.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • EHR's resulting from 9-1-1 response
  • Adult patients (aged 18+ at time of cardiac event)
  • experiencing out-of-hospital cardiac arrest (OHCA)
  • transported by an agency under OMD oversight
  • must have at least 2 EtCO2 values captured during care

排除标准

  • EHR's resulting from inter-facility scheduled or unscheduled medical transfers
  • pediatric patients (those aged <18 at time of incident) or unknown age
  • ROSC obtained prior to arrival of EMS
  • insufficient vital sign data

研究组 & 干预措施

stable ETCO2

low variation in measured end-tidal CO2 during cpr; low/high threshold yet to be determined

unstable/trending ETCO2

variability in end-tidal CO2 during CPR, with or without measurable trend

结局指标

主要结局

未指定

次要结局

  • Neurologically Intact Patient Survival(90 days)

研究者

发起方
Office of the Medical Director for EMS in Oklahoma City and Tulsa
申办方类型
Other
责任方
Principal Investigator
主要研究者

Anna Bailey

Biostatisitican

Office of the Medical Director for EMS in Oklahoma City and Tulsa

研究点 (1)

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