To check Effectivess of lycopene therapy versus cryotherpay for the treatment of oral leukoplakia
- Conditions
- Health Condition 1: null- Patient with biopsy proven cases of oral leukoplakia
- Registration Number
- CTRI/2016/04/006827
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 100
All healthy male and female between 15-60 years having oral leukoplakia (biopsy proven) reporting to department of oral and maxillofacial surgery , CDER AIIMS
2. Patients having size of primary lesion more than 1 cm.
3. Patient having history of tobacco chewing/smoking.
1.Patient having white lesion with negative history of tobacco use.
2.Patients with lesion of size less than 1 cm.
3.Patients with lesion associated with ulcero-proliferative growth or suspicious of squamous cell carcinoma.
4.Patients who are nursing or pregnant.
5.Patients with uncontrolled systemic disease.
6.Patient who are allergic to tomato and food products containing tomato extracts.
7.Patient not willing to quit the adverse habit.
8.Patient refuses to give consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare clinical response (reduction in size of leukoplakia patch) after lycopene therapy and cryotherapy in the <br/ ><br>management of oral leukoplakia.Timepoint: after 1 month and 3 month
- Secondary Outcome Measures
Name Time Method To see for the presence of any new localization/recurrence after therapyTimepoint: evaluation to be done after 3 month and 6 months