A comparative clinical trial study to evaluate combined effect of Nimbapatolpatra Kashaya –Aaragwadhapatra lepa With Aaragwadhavrukshak Kashaya- Aaragwadhapatra lepa in Dadru.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare combined effect of “Nimbapatolpatra kashya –Aaragvadgapatralepa†with “ Aaragvadhavrukshak kashaya – Aaragvadhapatra lepa†in Dadru.
研究概览
简要总结
Title-A comparative clinical trial study to evaluate combined effect of “Nimbapatolpatra Kashaya –Aaragwadhapatra lepa †With “Aaragwadhavrukshak Kashaya- Aaragwadhapatra lepaâ€in Dadru.
Skin diseases are mainly caused by the involvement of several micro organism where Tinea is one among them. Tinea/Ringworm infection is caused by a distinct class of fungi. They thrive in keratin layer of the epidermis, nails and hair. However, they do not invade the living epidermis. The serum fungal inhibitory factors in the extra vascular space prevent the penetration of the fungi in the living tissue. Several factors such as poor nutrition, unhygienic conditions, hot and humid climate, vocation promoting sweating and maceration, Diabetes mellitus, debilitating diseases, administration of corticosteroids and immunosuppressive agent,close and intimate contact with infected persons, animals and fomites predispose to ringworm infection. It should be noted that 10-15% of the general practitioners work with skin disorders. 5 out of 1000 people are suffering from Tinea infection. In contemporary Medical science, management of Tinea is carried out with usage of topical or systemic antifungal, corticosteroids. Long lasting usage produce the adverse effect also. Possible palliative treatment is with Ayurveda, which is effective. Since long year ago,major emphysis given on topical treatment by local applications of various drugs. But it seems that only topical treatment is unsatisfactory. This is an attempt to treat Tinea by giving systemic regimens and to find which drug work with great efficacy. Now in this era,there is large numbers of patients having skin disease and their number is increases day by day. In Charak Chikitsasthan, adhyay no.7 explains all about “Kushtha.â€and also that Nimbapatolpatra and aragvadhavrukshaka are kushthaghna property.So here an attempt to study on Dadru with title “A comparative clinical study to evaluate combined effect of “Nimbapatolpatra Kashaya –Aaragwadhapatra lepa †With “Aaragwadhavrukshak Kashaya- Aaragwadhapatra lepaâ€in Dadru.Due to this reason,this topic is selected.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients presenting with classical signs & symptoms of Dadru.
- •The patients of both gender irrespective of caste,socio-economic status,religion, community, etc.
- •Age group between 20-60 years.
- •Washout period for previous medicine (Ex.Antifungal drugs,etc.) is of 15 days.
排除标准
- •Patient on steroid treatment.
- •Extensive Tinea.
- •Tinea more than 2 years Tinea associated with other skin diseases.
- •Tinea Unguium and Tinea Incognito.
- •HIV infective patient.
结局指标
主要结局
To compare combined effect of “Nimbapatolpatra kashya –Aaragvadgapatralepa†with “ Aaragvadhavrukshak kashaya – Aaragvadhapatra lepa†in Dadru.
时间窗: 5 days
次要结局
- to compare combined effect of Nimbapatolpatra kashay- aaragwadhpatra lepa with aaragwadhvrukshak kashay-aaragwadhpatra lepa in dadru(40 days)