The effect of vitamin D on metabolic disorders in diabetic patients

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 90

Inclusion Criteria

Diabetes type2 in both sexes; 25 to 65 years; Serum 25 hydroxy vitaminD3 levels less than 30 nano grams per milliliter (ng/ml); Body mass index (BMI) between 25 to 35 kilograms per square meter (kg/m²); glycated hemoglobin (HbA1c) level less than 8.5%; Willingness to participate in the project
Exclusion criteria: Insulin consumption; Smoking or drinking alcohol at least once a week; Regular consumption of (at least once a week) herbal, antioxidant, multivitamin mineral, vitaminD3 and omega3 supplements; Taking birth control pills and Nonsteroidal antiiflammatory drugs (NSAIDs) in the last three months; Pregnancy and lactatin; Diagnosed diseases such as cancer, digestive diseases, liver and kidney diseases, autoimmune diseases, inflammation, hypothyroidism, polycystic ovarian syndrome; Changing usual and balanced diet with vegetarian diets or single product or any other unusual changes in the last three months; triglyceride levels more than 250 Milligrams per deciliter (mg/dl) and cholesterol more than 300 mg/dl; Exposure to sun and use of solarium for tanning up to 3 months before the start of the study; Taking medications affecting vitaminD3 metabolism such as Antiepileptic drugs and corticosteroids; Consuming less than 90% of supplements; Suffering from any acute illness; Any change in the type and amount of blood glucose lowering drugs

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sirtuin-1. Timepoint: Before and 8 weeks after intervention. Method of measurement: Laboratory Kit.;Irisin. Timepoint: Before and 8 weeks after intervention. Method of measurement: Laboratory Kit.;Insulin resistance. Timepoint: Before and 8 weeks after intervention. Method of measurement: HOMA-IR formula.;HbA1C. Timepoint: Before and 8 weeks after intervention. Method of measurement: Laboratory Kit.

Secondary Outcome Measures

Name	Time	Method
C reactive peptide. Timepoint: Before and 8 weeks after intervention. Method of measurement: laboratory Kit.;Oxidant indices. Timepoint: Before and 8 weeks after intervention. Method of measurement: laboratory Kit.;25 hydroxyvitaminD3. Timepoint: Before and 8 weeks after intervention. Method of measurement: laboratory Kit.;Fasting Insulin. Timepoint: Before and 8 weeks after intervention. Method of measurement: laboratory Kit.;Lipid profile. Timepoint: Before and 8 weeks after intervention. Method of measurement: laboratory Kit.;Inflammatory indices. Timepoint: Before and 8 weeks after intervention. Method of measurement: laboratory Kit.