Long-term Evolution of Risky Sexual Behaviors and Prevalence of Sexually Transmitted Infections Among Pre-Exposure Prophylaxis Users: A Retrospective Observational Study in Gironde, France
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 248
- 试验地点
- 6
- 主要终点
- Prevalence of Sexually Transmitted Infections (STIs) within the last three months
研究概览
简要总结
SAFER-PrEP investigates the long-term impact of Pre-Exposure Prophylaxis (PrEP) on risky sexual behaviors and Sexually Transmitted Infection (STI) prevalence among users in Aquitaine. The study aims to compare STI rates over the last three months between individuals on PrEP for over a year and those on PrEP for less than a year. This retrospective observational research offers insights into the evolving dynamics of sexual health practices, informing future PrEP prescriptions and enhancing preventive strategies.
详细描述
Scientific Rationale: The SAFER-PrEP study stems from the imperative to comprehend the intricate interplay between Pre-Exposure Prophylaxis (PrEP) utilization and sexual health dynamics. Amidst the increasing adoption of PrEP for HIV prevention, concerns arise regarding potential behavioral shifts and heightened risks for Sexually Transmitted Infections (STIs). The comprehensive investigation into these phenomena seeks to provide nuanced insights into the long-term implications of PrEP, contributing valuable data to public health initiatives and refining prevention strategies in the face of evolving sexual health landscapes.
Procedure: Participants, comprising individuals on PrEP for over a year and those for less than a year, will be engaged through a observational approach. Data will be collected via self-administered questionnaires during routine consultations for PrEP renewal in various medical settings, including hospitals and private practices. This comprehensive strategy enables a nuanced exploration of sexual behaviors and STI prevalence.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged over 18 years old;
- •Participants using PrEP for at least 6 months ;
- •French-speaking, without comprehension disorders ;
- •being affiliated to health insurance ;
- •Willing to participate and to sign informed consent.
排除标准
- •Individuals with known HIV positivity;
结局指标
主要结局
Prevalence of Sexually Transmitted Infections (STIs) within the last three months
时间窗: At baseline (Day 0)
次要结局
- Prevalence of risky sexual behaviors in the last three months.(At baseline (Day 0))
- Description of the population of PrEP users in Aquitaine.(At baseline (Day 0))
- Behavioral trends in PrEP users based on self-administered questionnaires.(At baseline (Day 0))
- Comparison of STI prevalence between PrEP users for over a year and those for less than a year.(At baseline (Day 0))