The Compass Trial.
Recruiting
- Conditions
- contrast induced acute kidney injury (CI-AKI)
- Registration Number
- NL-OMON29471
- Lead Sponsor
- eiden University Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 575
Inclusion Criteria
1. Patients with an eGFR (estimated glomerular filtration rate 30-45 ml/min);
2. Patients with an eGFR 45-60 ml/min and diabetes mellitus (either type 1 or 2);
Exclusion Criteria
1. eGFR < 30 ml/min;
2. Age < 18 years;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean relative increase in serum creatinine.
- Secondary Outcome Measures
Name Time Method 1. Incidence of CIN;<br /><br>2. Recovery of renal function 2 months after CT in patients who developed CIN;<br /><br>3. Mean relative increase in serum creatinine 7-14 days after contrast administration;<br /><br>4. Acute kidney injury according to the serum creatinine based RIFLE criteria;<br /><br>5. The need for dialysis;<br /><br>6. (Re)hospitalisation, duration of hospitalisation in the two months following randomisation;<br /><br>7. Visits to the outpatient clinic in the two months following randomisation.