Small vessel assessment to guide early hospital discharge following acute heart attack
Phase 2
- Conditions
- Acute myocardial infarctionCirculatory System
- Registration Number
- ISRCTN56383403
- Lead Sponsor
- ewcastle upon Tyne Hospitals NHS Foundation Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 122
Inclusion Criteria
Patients aged 18-90 years presenting with ST-segment elevation myocardial infarction (STEMI)
Exclusion Criteria
1. Patients in whom safety or clinical concerns preclude participation
2. Pregnant or breastfeeding female
3. Suboptimal angiographic results such as final slow flow or distal embolization
4. Need for in-hospital staged percutaneous coronary intervention (PCI)
5. Cardiogenic shock
6. Pulmonary oedema or severe heart failure requiring diuretics treatment during or immediately after the procedure
7. Contraindication to adenosine
8. Standard contra-indications to MRI such as claustrophobia
9. Known allergy to any other component of xience stent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eft ventricle function (strength of heart muscle) measured using cardiac magnetic resonance imaging.at 3 months
- Secondary Outcome Measures
Name Time Method 1. Clinical events measured using GP/ hospital records and patient contact at 1 year<br>2. Clot volume during acute heart attack measured using optical coherence tomography at the time of acute heart attack presentation<br>3. Health status measured using Seattle questionnaire at 3 months