Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District

Completed

• Conditions: Antibiotic Side Effect
• Interventions: Other: Antibiotic KAP questionnaire

• Registration Number: NCT04127682
• Lead Sponsor: Assiut University

Brief Summary

Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic resistance. It is important to study physicians' antibiotic prescribing behavior to understand its determinant and for further planning of appropriate interventions to optimize antibiotic prescription.

Detailed Description

Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic resistance.

In Egypt, a recent study conducted in El-Minya governorate to investigate antibiotic use in PHC centres and in governmental hospitals, revealed that physician prescriptions of antibiotics for ARIs were extremely high as 82% of pediatric visits for ARIs resulted in an antibiotic prescription. Most of these infections are caused by viruses and do not require antibiotic treatment.

Numerous interventions to improve antibiotic prescribing practices have been reported from various countries with varying results. No single intervention appears to have superior efficacy, but combinations of interventions are typically more effective, and strategies that target health care professionals and/or patients (or parents of young children) have achieved success at reducing antibiotic prescriptions for ARIs.

Despite the emergence of antibiotic resistance and international efforts to reduce antibiotic use, prescription still high and inappropriate. Children are a vulnerable group and inappropriate antibiotic prescription may affect their health and may contribute to development of many diseases as allergies beside emergence of antibiotic resistance. Also, most of acute respiratory infections in children are viral infections and they receive antibiotic for it. So,, it is important to study physicians' antibiotic prescribing behavior to understand its determinant and for further planning of appropriate interventions to optimize antibiotic prescription.

Study Timeline

• Study First Submitted: 2019-10-13
• Study First Submitted QC: 2019-10-14
• Study First Posted: 2019-10-15
• Study Start: 2021-01-01
• Primary Completion: 2022-07-30
• Study Completion: 2022-10-30
• Status Verified: 2022-11
• Last Update Submitted: 2022-11-04
• Last Update Posted: 2022-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 186

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Physicians	Antibiotic KAP questionnaire	Physicians dealing with cases of pediatrics' acute URIs at PHC units either urban or rural, insurance hospitals or Assiut university hospitals.

Primary Outcome Measures

Name	Time	Method
Physicians knowledge of antibiotic resistance	6 months	By self administered questionnaire
Attitude and practice of physicians as regard antibiotic prescription in pediatric cases of acute upper respiratory tract infections.	6 months	By self administered questionnaire

Secondary Outcome Measures

Name	Time	Method
Determinants of physicians' antibiotic prescribing behavior in cases of acute upper respiratory tract infection in children.	6 months	By self administered questionnaire

Trial Locations

Locations (1)

Faculty of medicine- Assiut university; 🇪🇬 Assiut, Egypt