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Establishment of Surgical Audit System for Overall Survival following Gastric Cancer Resectio

Not Applicable
Conditions
Patients who underwent gastric cancer resection
Registration Number
JPRN-UMIN000014284
Lead Sponsor
ational Hospital Organization Kumamoto Medical Center
Brief Summary

We included 2045 patients for analysis. The median (95% confidence interval) follow-up time was 5.1 (1.2-6.8) years for censored patients. Although EPOS-GC demonstrated a good discriminative power (Harrell's C-index, 95% confidence interval: 0.80, 0.79-0.83), the calibration plot revealed that EPOS-GC underestimated 5-year survival rates in the high-risk group. Therefore, we recalibrated the model with Cox's regression analysis. The recalibrated EPOS-GC showed a good calibration, preserving the high discriminative power (C-index, 95% confidence interval: 0.80, 0.78-0.82). The O/E among hospitals according to the recalibrated EPOS-GC ranged between 0.87 and 1.27. The O/E correlated with hospital volumes (Spearman's correlation = 0.76, n = 11, p = .006).

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
2000
Inclusion Criteria

Not provided

Exclusion Criteria

1) those who underwent emergency operations, 2) those who had received preoperative chemotherapy, 3) those who had non-epithelial tumors in stomach, such as malignant lymphoma, carcinoid, or gastrointestinal stromal tumor, 4) those who had a past history of treating other malignancies, 5) those who had other malignancies than gastric cancer at the time of operation.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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