A randomized trial comparing longstanding indwelling pleural catheters with pleurodesis as a frontline treatment for malignant pleural effusion.
Phase 3
Completed
- Conditions
- malignant pleural effusion10038666
- Registration Number
- NL-OMON34219
- Lead Sponsor
- Antoni van Leeuwenhoek Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
symptomatic pleural effusion
any histologically or cytologically proven malignancy
written informed consent
recurrence of pleural effusion within 6 months after last therapeutic thoracentesis
* written informed consent (part 2)
Exclusion Criteria
other causes of pleural effusion than malignancy
previous chemical or surgical pleurodesis
impaired immunity: leucopenia <2.0 x 109/L, high dose corticosteriods (>=1mg/kg)
thrombocytopenia (< 50 x 109/L)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method