Deep breaths and airway closure in asthma

Phase 2

Withdrawn

• Conditions: Asthma; Respiratory - Asthma

• Registration Number: ACTRN12605000790640
• Lead Sponsor: Woolcock Institute of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-12-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Asthma, defined by previous doctor diagnosis and current symptoms or regular therapyNon-asthmatic controls with no history of asthma or other chronic respiratory disease.

Exclusion Criteria

Smokers and subjects who are otherwise unsuitable for bronchial challenge will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The fall in the forced expiratory volume in one second, with and without deep inspirations.[Measured 60 seconds after bronchial challenges with methacholine, after active and control treatments.]

Secondary Outcome Measures

Name	Time	Method
The bronchoprotective effect of deep inspiration, measured by the difference in response between tests with and without deep inspirations, after active and control treatments.[]