Treatment of Splenic Trauma: a Retrospective Cohort Study

Completed

• Conditions: Splenic Injury
• Interventions: Procedure: Treatment of splenic injury

• Registration Number: NCT01965548
• Lead Sponsor: University Hospital of North Norway

Brief Summary

In blunt trauma, the spleen is most frequent injured organ in the abdomen and the most frequent source of bleeding in the abdomen.

Historically, splenectomy was the treatment of choice for splenic bleeding. For exsanguinating patients, open splenectomy is still the proper choice of treatment if the spleen is a significant source of bleeding. However, for hemodynamic stable patients with splenic injury, non-operative management (NOM) is an alternative, assuming they have no other indication for surgery (peritonitis).

Non-operative management includes observation and/or splenic artery embolisation (SAE), but the indications for observation and SAE varies between trauma centers. The greatest advantage of NOM is the preservation of splenic function.

In the investigators hospital splenic artery embolisation was introduced in 2007. The investigators want to describe the treatment of splenic injuries in their hospital, to see if the number of splenectomies has been recduced after 2007, and to see if SAE has also been used in transferred trauma patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-10-15
• Study First Submitted QC: 2013-10-17
• Study First Posted: 2013-10-18
• Study Start: 2014-09
• Primary Completion: 2015-10
• Study Completion: 2015-10
• Status Verified: 2015-12
• Last Update Submitted: 2016-01-08
• Last Update Posted: 2016-01-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 109

Inclusion Criteria

• All patients admitted at UNN Tromsø in the period of 01.01.2000 - 31.12.2013 and with the discharge diagnosis S36.0 Splenic injury (ICD-10)

Exclusion Criteria

• no injury/coding error
• iatrogenic injury
• transfer >7 days after injury
• >10 days between injury and first hospital admission

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Splenic injury	Treatment of splenic injury	All patients admitted at the University Hospital North Norway Tromsø with a splenic injury following trauma, are included in the study.

Primary Outcome Measures

Name	Time	Method
type of splenic trauma treatment	0-7 days	There are three different treatments of splenic trauma treatment, resulting in four different treatments: * splenectomy; * splenic artery embolization; * non-operative management; * any combination of the three treatments

Secondary Outcome Measures

Name	Time	Method
Mortality	30 days
Length of stay in the intensive care unit	0 - 90 days
Emergency procedures	0 - 7 days	Emergency procedures includes: * Chest tube insertion; * Hemostatic surgery in the abdomen; * Hemostatic surgery in the pelvis with packing; * Thoracotomy; * Primary stabilization of fractures (external fixation); * Endotracheal intubation
Length of hospital stay	1 - 90 days

Trial Locations

Locations (1)

University Hospital North Norway Tromsø; 🇳🇴 Tromsø, Norway