Echocardiography Guided Optimisation of Cardiac Resynchronization Therapy Late after Implantatio

Not Applicable

Completed

• Conditions: Heart Failure; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12612000805875
• Lead Sponsor: Cardiac Imaging Group, University of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-08-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

We studied individuals who had undergone CRT implantation and were able to perform moderate exercise to level of completion of 6 minute walk test.

Exclusion Criteria

Unable or unwilling to consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional improvement assessed using standard heart failure mechanisms - 6 minute walk distance, treadmill time, peak oxygen consumption on exercise (VO2 max), brain natriuretic peptide (BNP).[6 and 12 months]

Secondary Outcome Measures

Name	Time	Method
Echocardiographic improvement in terms of ventricular function and ventricular synchrony. We will measure Simpsons biplane ejection fraction as a measure of left ventricular function and compare change from the start of each stage to the end. we will use the standard deviation fo the time to peak systolic contraction as a measure of left ventricular dyssychrony. Again we will compare change from the start of each stage to the end.[6 and 12 months]