The effects of respiratory muscle training on neural respiratory drive and cardiac autonomic function in patients submitted to open-heart surgery
Phase 2
Completed
- Conditions
- Postoperative pulmonary dysfunction and impaired cardiac vagal modulation are reported after cardiac surgery whereas respiratory muscle training (RMT) has also been proved as a complementary technique to improve respiratory muscle and cardiac autonomic properties. However, the efficacy of RMT technique has not been investigated in patients who had undergone open-heart surgery.Respiratory muscle training, Neural respiratory drive, Cardiac autonomic function, Heart rate variability, Open-heart surgery
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
All the participants aged 35 to 65 years who were admitted to Thammasat University Hospital, Thailand, for coronary artery bypass graft or heart-valve surgery
Exclusion Criteria
Participants were excluded if they had a history of prior cardiac surgery, heart failure, uncontrolled blood pressure, uncontrolled diabetes mellitus, pulmonary diseases, neurological disorders, body mass index greater than 35 kg/m2, or required mechanical ventilator support for more than 24 hours postoperatively
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eural respiratory drive (NRD) sEMGpara was measured at rest while patients perform normal tidal breathing for one minute (sEMGpara tidal) and collected during execute a maximal static inhalation (sEMGpara max) NRD was acquired by measuring surface parasternal intercostal electromyogram (sEMGpara) using a wireless EMG system (TeleMyo 2400T G2, Noraxon USA Inc., Scottsdale, AZ, USA)
- Secondary Outcome Measures
Name Time Method Heart rate variability (HRV) HRV was measured while performing a 1-minute paced deep breathing maneuver HRV was recorded using a V800 Polar monitor (Polar Electro Ltd., Kempele, Finland) and analyzed by Kubios HRV software v. 3.0.2