The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy

Not Applicable

Completed

• Conditions: Adenoma
• Interventions: Other: segmental reexamination

• Registration Number: NCT03268200
• Lead Sponsor: The Catholic University of Korea

Brief Summary

The aim of this study was to determine whether segmental re-examination of the each segment (right colon, mid-colon, and left colon) could increase the proximal adenoma detection rate (ADR) and to evaluate the time-effectiveness of this approach.

Detailed Description

The investigators prospectively recruited patients (aged ≥45 and ≤75 years) who were scheduled to undergo colonoscopy at our center. Patients were excluded if they had advanced colonic cancer, prior resection of the proximal colon, inflammatory bowel disease, or polyposis syndrome, or were unable to provide informed consent. In addition, if the quality of bowel preparation was unsatisfactory (Boston Bowel Preparation Scale \[BBPS\] score \<2 in any segment of the colon), or if the cecum could not be intubated during the colonoscopy, patients were excluded.

A randomization list was generated with the randomization algorithm of random sorting, using Excel program. Included patients were randomly assigned to one of the two groups: segmental re-examination group, in which the each segment (right colon, mid-colon, and left colon) was examined twice segmentally; or control group, in which the withdrawal time in the each segment was about 2 minutes.

Study Timeline

• Study First Submitted: 2017-08-29
• Study First Submitted QC: 2017-08-29
• Study First Posted: 2017-08-31
• Study Start: 2017-09-01
• Primary Completion: 2019-06-30
• Study Completion: 2019-12-31
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-24
• Last Update Posted: 2023-07-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 450

Inclusion Criteria

• Patients (aged ≥45 and ≤75 years) who were scheduled to un- dergo colonoscopy

Exclusion Criteria

• Patients who had advanced colonic cancer, prior resection of the proximal colon, inflammatory bowel disease, or polyposis syndrome, or were unable to provide informed consent.
• If the quality of bowel preparation was unsatisfactory (Boston Bowel Preparation Scale [BBPS] score <2 in any segment of the colon), or if the cecum could not be intubated during the colonoscopy, patients were excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Case group	segmental reexamination	Each segment of colon (right colon, mid-colon, and left colon) was examined twice

Primary Outcome Measures

Name	Time	Method
Adenoma detection rate	7 days

Secondary Outcome Measures

Name	Time	Method
Withdrawal time	1 days
per-patient polyp detection rate	7 days
Per-patient adenoma detection rate (ADR) at each segment of colon	7 days

Trial Locations

Locations (1)

Incheon St. Mary's hospital, Catholic university of Korea; 🇰🇷 Incheon, Korea, Republic of