Effect of pyridostigmine in post-stroke dysphagia

Phase 1

Recruiting

• Conditions: Dysphagia following cerebral infarction.; Dysphagia following cerebral infarction; I69.391

• Registration Number: IRCT20210216050383N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Patients with ischemic stroke revealed by CT scan or MRI 14 to 180 days before intervention
and diagnosed to have post-stroke dysphagia according to MASA score(more than 177) and PSR time(more than 1.5 s) assessed by a speech pathologist.

Exclusion Criteria

Younger than 18
Hemorrhagic stroke
Stroke onset before 14 days or after 180 days
Head and/or neck injuries

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Grade of patients dysphagia according to Mann Assessment of Swallowing Ability score sheet. Timepoint: Measuring the score of Mann Assessment of Swallowing Ability questionnaire in patients at the beginning of the study (before the intervention) and 30 days after the use of pyridostigmine. Method of measurement: Mann Assessment of Swallowing Ability questionnaire.;Pharyngeal swallowing Reflex time. Timepoint: Measurement of pharyngeal swallowing reflex time in patients at the beginning of the study (before the intervention) and 30 days after the use of pyridostigmine. Method of measurement: Assessed by Speech pathologist bedside.