NCT05012228招募中不适用
Molecular Mechanisms of Fibrillin/LTBP Superfamily in Renal Fibrosis and Cardiorenal
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Expression of LTBP4 in human renal fibrotic tissue
研究概览
简要总结
This project is to understand the LTBP4 expression in human renal fibrotic tissues. The investigators will exam major location of LTBP4 expression and check any similar or discrepancy in renal fibrosis with different etiologies.
详细描述
The investigators will obtain the residual renal tissues with different etiologies and check the expression of LTBP4. The location and quantitation of LTBP4 in renal tissues will be checked. It will be great to understand the association between the severity of fibrosis and the expression of LTBP4 and other matrix proteins.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Abnormal kidney function, proteinuria, hematuria
排除标准
- 未提供
结局指标
主要结局
Expression of LTBP4 in human renal fibrotic tissue
时间窗: 5 years
Expression of biomarkers in human renal fibrotic tissue
时间窗: 5 years
Potential markers: eg. ROS-related proteins (8-oxodG, 4-HNE)
次要结局
未报告次要终点
研究者
研究点 (1)
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