Assessment of effect of Black Turmeric and aloe vera loaded calcium carbonate nanoparticle laden insitu gel in management of oral submucous fibrosis. A randomized clinical trial.

Saveetha dental college and hospital0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年6月26日

试验速览

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•Both male & Female in equal ratio of total 400 patients will be selected. OSMF staging based on KERR et al (2011) and Passi et al (2017) criteria.
•divided in 5 groups based on age.
•1. Patients with Oral submucous fibrosis confirmed both clinically and histologically (Grade III)
•2. Patients who are ready to quit the habit of Gutkha, Arecanut, Smoking, Tobacco and accepted for regular follow ups.
•3. Patient with chief complaint of reduced mouth opening along with burning sensation and reduced tongue protrusion.
•PRIMARY OBJECTIVES:
•To evaluate the efficiency of Black turmeric and Aloe Vera Calcium carbonate nanoparticle in-situ gel for improving mouth opening in OSMF.
•SECONDARY OBJECTIVES:
•To evaluate the efficiency of Black turmeric and Aloe Vera Calcium carbonate nanoparticle in-situ gel for improving burning sensation in OSMF
•To evaluate the efficiency of Black turmeric and Aloe Vera Calcium carbonate nanoparticle tongue protrusion in OSMF

•1.Pregnant women and lactating mothers
•2. Oral Submucous Fibrosis (OSMF) patients with early, mild and advanced condition.
•3. Patients having concomitant disease with restricted mouth opening /burning sensation.
•4. Patients with malignant lesions, systemic disorders like diabetes, thyroid, hypertension etc.

发起方

Saveetha dental college and hospital