Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling

Phase 2

• Conditions: Single Root Teeth; Necrotic Pulp
• Interventions: Drug: resin sealer; Drug: bioceramic sealer; Drug: MTA

• Registration Number: NCT05419752
• Lead Sponsor: Cairo University

Brief Summary

aim of the study will be conducted to compare the effect of MTA fill apex sealer and endo sequence bioceramic sealer in obturation on the intenisty of postoperative pain and the incidence of post operative swelling in patient with necrotic teeth .

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-05-27
• Status Verified: 2022-06
• Study First Submitted QC: 2022-06-13
• Last Update Submitted: 2022-06-13
• Study First Posted: 2022-06-15
• Last Update Posted: 2022-06-15
• Study Start: 2022-07-30
• Primary Completion: 2022-08-30
• Study Completion: 2022-08-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients requiring root canal treatment of single canal necrotic teeth.
• Patient from 18 to 60 years old
• Patients with Asymptomatic apical periodontitis.
• Teeth presenting with no clinical symptoms and with a periapical score from 2 to 4 according to Orstavik et al

Exclusion Criteria

• Teeth with incompletely formed apex

  • Teeth requiring retreatment
  • Patients having complicating systemic disease such as diabetes, malignancy, pregnancy, central nervous system disorders, Cardiovascular system disorders, respiratory disorders, asthma patients, psychiatric disorders, immunocompromised patients
  • Patients taking anti-inflammatory or antibiotics
  • Patients giving history of analgesic or antibiotic intake 1 week before treatment
  • Patients below 18 years of age

• Patients above 65 years of age

  • Patients having history of peptic ulcer or gastrointestinal bleeding
  • Teeth affected with periodontal disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
AH plus resin sealer	resin sealer	obturation using AH Plus sealer
endo sequence bioceramic sealer	bioceramic sealer	obturation using Endo-sequence BC sealer
MTA fill apex calcium silicate base sealer	MTA	obturation using calcium-silicates based MTA fill-apex sealer

Primary Outcome Measures

Name	Time	Method
Intensity of post-operative pain	72 hours	Measurement of post-operative pain by Visual analogue scale

Secondary Outcome Measures

Name	Time	Method
post operative swelling	24 hours	Yes or no yes or no