Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appendectomy
- Conditions
- Laparoscopic SurgeryAppendicitis Acute
- Interventions
- Device: Technique used for closing the appendiceal stump
- Registration Number
- NCT04083313
- Lead Sponsor
- University Hospital Dubrava
- Brief Summary
In this randomized control trial the patients with acute appendicitis will be divided in three groups according to the management of the appendiceal stump(Endostapler, Endoloop or Endoclip). Pre-, peri- and postoperative data will be analysed.
- Detailed Description
Acute appendicitis is the most common indication for intraabdominal emergency surgery, and appendectomy is one of the most commonly performed procedures in abdominal surgery. Today laparoscopic appendectomy (LA) has the status of a ''Gold Standard'' treatment, and it is accepted as the treatment of choice for acute appendicitis.There are several ways of closing the appendiceal stump.An inadequate closure of the appendiceal stump can lead to morbidity of operated patients. The aim of this study is to assess the efficiency of different closure techniques by focusing on the intraoperative and postoperative complications.The patients will be divided into three groups based on the technique used for appendiceal stump closure, whether it is Endoloop, Endostapler or Endoclip. In the patients included in the study the investigators will analyse demographic data, peroperative laboratory values, clinical data and treatment outcomes. Also, the histopathological findings of the specimens and perioperative and postoperative complications will be analysed.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 300
- Patients with clinically and radiologically(Ultrasound) verified appendicitis
- Patients converted from laparoscopy to open surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Endoclip Technique used for closing the appendiceal stump Patients in which appendiceal stump was ligated using Endoclip Endoloop Technique used for closing the appendiceal stump Patients in which appendiceal stump was ligated using Endoloop Endostapler Technique used for closing the appendiceal stump Patients in which appendiceal stump was ligated using Endostapler
- Primary Outcome Measures
Name Time Method Operative and postoperative complications Seven postoperative days Complications will be presented as a percentage of the all operated patients.
- Secondary Outcome Measures
Name Time Method Height Before surgery Meters
Weight Before surgery Kilograms
Duration of symptoms Before surgery Duration of symptoms will be measured in hours.
Value levels of leukocytes Before surgery Whit blood cells count
Neutrophiles Before surgery Neutrophile count
C-reactive protein Before surgery Milligrams/liter
Body mass index Before surgery Kilograms/meter square
Body temperature Before surgery Body temperature will be measured in degrees celsius.
Length of the operations During operation Length of the operations will be presented in minutes.
Closure of the appendiceal stump using Endoloop During operation Percentage of the all operated patients in which this technique was used.
Closure of the appendiceal stump using Endostapler During operation Percentage of the all operated patients in which this technique was used.
Closure of the appendiceal stump using Endoclip During operation Percentage of the all operated patients in which this technique was used.
Number of reoperated patients Seven days Presented in total numbers
Hospital stay Seven days Length of the hospital stay will be presented in days.
Histopathological findings Seven days Histopathological findings will be graduated in 3 grades - phlegmonous,gangrenous and perforated.
Percentage of reoperated patients Seven days Presented in percentages
Trial Locations
- Locations (1)
UH Dubrava
🇭🇷Zagreb, Croatia