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临床试验/CTRI/2025/08/093285
CTRI/2025/08/093285尚未招募2 期

An open label randomized controlled trial to evaluate the efficacy of Kanaka tail nasya with and without local application on face in the management of Vyanga

Institute for Ayurved Studies and Research Shri Krishna AYUSH University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年11月3日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
Change in the grade of MASI (Melasma area severity index) score of Melasma.

研究概览

简要总结

It is an open label randomized controlled trial to evaluate the efficacy of Kanaka Tail Nasya with and without local application on face in the Management of Vyanga .Vyanga, can be characterized by melasma, manifests as distinct light to dark brown patches of varying shapes and sizes, primarily on sun-exposed areas like cheeks, nose, forehead, and chin. There are two groups, having 20 patients in each group. In group A, only kanaka tail nasya will be given to patient for total 14 sittings (7 sittings than 7 days gap and further 7 sittings ). Similarly in group B , nasya will be given along with local application of kanaka tail over face. After treatement , changes will be observed as per subjective criteria and objective criteria( size, no., colour of patches, MASI score) . On the basis of outcomes and by using statistical tools, result will be concluded.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
25.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • Patients having classical signs and symptoms of vyanga irrespective of gender,religion and economical status.Age group:25 years to 45 years.
  • Patients fit for nasya karma and abhyanga.Patients willing to sign the consent form.

排除标准

  • Vyanga caused due to any known systemic disease like Addison’s disease, cushing’s syndrome.
  • Patients with known case of secondary systemic involvement like cardiac diseases etc.Vyanga along with kushta roga to be excluded.Hyper pigmentation caused by known case of tumour like malignant melanoma.Pregnant, mensurating and lactating women.Patient not fit for nasya karma and abhyanga.

结局指标

主要结局

Change in the grade of MASI (Melasma area severity index) score of Melasma.

时间窗: 1st - 0 Day | 2nd - After completion of total 14 sittings | 3rd - on follow up

次要结局

  • Change in Colour, Size and Number of Mandalas.(Change in lakshanas like Kandu, Rukshta of skin.)

研究者

发起方
Institute for Ayurved Studies and Research Shri Krishna AYUSH University
申办方类型
Other [Government Ayurvedic College and Hospital]
责任方
Principal Investigator
主要研究者

Parth Kumar

Institute for Ayurved Studies and Research Shri Krishna AYUSH University

研究点 (1)

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