Effect of buffered vs non-buffered local anesthetic solution on pain perception and onset of anesthesia in children.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Pain perception and time of onset of anesthesia
研究概览
简要总结
Introduction
Dental anxiety and fear of needle injection is one of the most common problems encountered by dental practitioners, especially in the pediatric patient. Several methods are suggested to lower the discomfort of local anesthesia injection during dental procedures. There are some technical advances to lower the pain of injection by alkalization of dental anesthetics prior to injection.
Aim:
This study aims to evaluate the efficacy of pH buffering of local anesthetic drug, on the pain,discomfort and onset of local anesthesia injection during dental procedures.
Children divided randomly in 2 groups- Test group and Control Group
Group 1 – Test group-The test solution -alkalinized 2% lidocaine/ epinephrine 1:100,000 is administered before the dental treatment.
Group 2- Control group- non-alkalinized 2% lidocaine/epinephrine 1:100,000 is administered before the dental treatment.
Pain perception during the administration of local anesthesia, the time of onset and efficacy of analgesia assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 6.00 Year(s) 至 10.00 Year(s)（—）
- 性别
- All
入选标准
- •patients between 6-10 years of age who had not undergone any prior dental treatment, requiring bilateral IANB and exhibited Frankl behavior rating grade 3 or 4.
排除标准
- •Patients who were allergic to local anesthesia; had medically-compromised condition or, History of dental treatment.
结局指标
主要结局
Pain perception and time of onset of anesthesia
时间窗: Same day , 1 week
次要结局
- efficacy of analgesia(same day, after 1 week)
研究者
Dr Harsha Kewlani
College of Dental sciences and research centre, Bopal