Evaluation of the effects of a low free sugar diet in patients with Nonalcoholic fatty liver disease
- Conditions
- onalcoholic fatty liver disease.low free sugar diet, lipid profile, glycemic indices, liver enzymes, inflammatory factors, hepatic steatosis , fibrosis , patients with Nonalcoholic fatty liver disease
- Registration Number
- IRCT20100524004010N30
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 42
The desire to participate in research
Age 60-18 years
BMI above 20
Evidence of non-alcoholic steatohepatitis (inflammation and swelling of hepatocytes) second and third degree in ultrasonography
Evidence of non-alcoholic steatohepatitis in fibro-scan results with CAP Score over 263
Lack of a history of alcohol consumption or alcohol consumption less than 10 grams per day in women and less than 20 grams per day in men
Lack of other chronic and acute liver diseases and disorders (hepatitis B, C, etc.), biliary disease, autoimmune diseases, cancer and hereditary disorders affecting the condition of the liver (iron, copper storage disease) and cirrhosis
Lack of pregnancy or lactation in women
No consumption of hepatotoxic drugs such as phenytoin, tamoxifen and lithium, and drugs that affect liver function
Lack of desire to continue research
Forced to use antibiotics or hepatotoxic drugs during the study
Non-compliance with low free sugar diet
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hepatic steatosis, Liver fibrosis. Timepoint: At the first and at the 12th week of the study. Method of measurement: Fibroscan.
- Secondary Outcome Measures
Name Time Method