ChiCTR-IPR-17013365Not yet recruitingPhase 4
肥胖患者围术期精准药物治疗的方案比较
自筹1 site in 1 country200 target enrollmentStarted: December 1, 2017Last updated:
Trial Snapshot
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- 奥美拉唑的血药浓度
Study Overview
Brief Summary
本研究旨在揭示质子泵抑制剂（以奥美拉唑注射剂为代表）的不同给药方式对围术期肥胖症患者的药代动力学改变，以及临床疗效的对比观察，为此类患者提供安全有效的用药推荐。
Study Design
- Study Type
- 干预性研究
- Primary Purpose
- 随机平行对照
Eligibility Criteria
- Ages
- 18 to 50 (—)
- Sex
- All
Inclusion Criteria
- •① 接受袖状胃切除术或胃转流术术后的肥胖症患者（BMI≥26kg／m2）
Exclusion Criteria
- •有长期质子泵抑制剂用药史的患者
Arms & Interventions
A
奥美拉唑持续静脉推注
B
奥美拉唑静脉滴注
Outcomes
Primary Outcomes
奥美拉唑的血药浓度
Time Frame: 用药前（0h）以及用药后 24h
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Not yet recruiting
Phase 2/3
A comparative clinical trial to study the efficacy of Asana Churna and Guduchyadi Churna in the management of Sthaulya (Overweight)in children of age group 10 to 16 Years.CTRI/2025/07/090336PDEAs College of Ayurved and Research Centre Nigdi Pune64
Active, not recruiting
Phase 1/2
IBI362 15mg 在中-重度肥胖患者中的耐受性和药代 / 药效动力学研究CTR2025182298
Recruiting
Phase 3 4
Clinical trial on body fat loss in overweight subjectsCTRI/2025/01/079489Daehan chemtech co., Ltd.150
Unknown
Not Applicable
基于 PPK/PBPK 模型评估胃袖状切除术对奥美拉唑药动学的影响ChiCTR2100046578湖南省卫生计生委科研课题（20201656）50
Active, not recruiting
Not Applicable
兰索拉唑肠溶胶囊在健康研究参与者中的生物等效性研究CTR2025482460