COMPARISION OF ONSET TIME OF SENSORY BLOCK WITH 0.5% and 0.375% ROPIVACAINE IN USG GUIDED INFRACLAVICULAR BRACHIAL PLEXUS BLOCK
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To compare the time of onset of sensory block between 0.5% and 0.375 % ropivacaine
研究概览
简要总结
Infraclavicular brachial plexus block provides sufficient anesthetic and analgesic effect for lower arm surgery (3).Infraclavicular approach also has a short procedure time compared to other approaches including supraclavicular and axilliary approaches ( Therefore ultrasound- guided infraclavicular brachial plexus block has been increasingly used . At centres with high volume of patient load ,onset time is one of the most important considerations for choosing a local local anaesthetic drug.To hasten the time of onset of the block ,higher concentration of local anaesthetics are used (8) .However higher concentration of local anesthetics causes direct neurotoxicity to the neurons .The volume and concentration of the drug must be carefully selected to avoid exceeding the maximal dose. (9)Thus, the use of diluted local anesthetics may be safer .Therefore we aimed to compare the onset times of 0.5% and0.375% ropivacaine for infraclavicular brachial plexus block
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients age group 18 to 65 years ,of all sexes 2, ASA grade 1 and 2 3.patient with elective orthopedic surgery for arm,elbow,forearm and hand under US –guided infraclavicular approach 4.Patient who are willing to give informed and written consent for the surgery.
排除标准
- •1.Patient refusal for infraclavicular brachial plexus block 2.Patient with brachial plexus neuropathies,diabetes ,any known peripheral neuropathic disease,post CVA 3.severe brochopulmonary disease 4.coagulopathies
- •severe cardiac diseases 6.pregnancy 7.intolerance or known history of allergy to one or more medications of the study 8.Patient undergoing emergency surgeries 9 local infection at the site of the block.
结局指标
主要结局
To compare the time of onset of sensory block between 0.5% and 0.375 % ropivacaine
时间窗: To compare the time of onset of sensory block between 0.5% and 0.375 % ropivacaine in orthopedic patients within 30 minutes of performing the block prior to Surgery at baseline
次要结局
- 1.To compare the onset time of motor block(2.Intraoperative hemodynamics ,)
研究者
Dr Saurav Kalita
Gauhati Medical College and Hospital