Efficacy of zinc as an adjunct therapy in the management of severe pneumonia among Gambian childre
Completed
- Conditions
- Severe and very severe pneumonia defined clinicallyRespiratoryPneumonia
- Registration Number
- ISRCTN33548493
- Lead Sponsor
- Medical Research Council (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 600
Inclusion Criteria
Prior to 18/10/10:
Children aged 2-59 months presenting with severe or very severe pneumonia to the MRC Hospital or the Royal Victoria Teaching Hospital, Banjul.
Modified on 18/10/10:
'Children aged 2-59 months presenting with severe or very severe pneumonia to the MRC Hospital, the Royal Victoria Teaching Hospital, Banjul, and the health centres at Fajikunda, Brikama, Serekunda and Basse.
Exclusion Criteria
Children with severe malnutrition or signs of systemic infection other than pneumonia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Treatment failure at 5 days
- Secondary Outcome Measures
Name Time Method The following will be assessed after 6 months supplementation of zinc or placebo in a subgroup: <br>1. Time to resolution of signs of severe and very severe pneumonia<br>2. Length of admission<br>3. Height<br>4. Multi-antigen skin testing