Effect of Aloe Vera Gel as an Intra Canal Medicament in Patients With Asymptomatic Periapical Lesions.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Presence or absence of signs and symptoms of the patient
研究概览
简要总结
This research will overview the effect of aloe vera gel (AVG) as intra canal medicament in patients with asymptomatic periapical lesions. It will provide endodontists with scientific evidence regarding the beneficial use of AVG as an intracanal medicament owing to its superior antibacterial and analgesic properties as compared to routinely used commercial intra canal medicaments.
详细描述
Objective
To evaluate the effect of aloe vera gel based on clinical signs and symptoms as an intracanal medicament in asymptomatic periapical lesions over a period of three weeks. Methodology: Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions in group A while in group B (control group) no intracanal medicament will be placed. Patients will be randomly divided into two groups by randomization in Statistical Package for Social Sciences software (SPSS v24.0). They will be recalled for one week and three week follow ups and in case of no clinical signs and symptoms endodontic procedure will be completed. Statistical analysis: Descriptive statistics will be used for reporting age. Frequencies and percentages will be calculated for categorical variables and intergroup comparison will be done by chi square test
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Both male and female patients presenting with asymptomatic periapical lesions in permanent teeth
排除标准
- •History of allergy to AVG
- •Comorbidities likely to impair healing
- •Pregnant women
- •History of previous endodontic treatment in the same tooth
- •Presence of pulp calcification
- •Internal or external root resorption
研究组 & 干预措施
Intervention Group
Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions
干预措施: Aloe vera Gel (Biological)
结局指标
主要结局
Presence or absence of signs and symptoms of the patient
时间窗: One week and 3 weeks
Patients in both the groups will be recalled after one week. They will be assessed clinically for either presence or absence of signs and symptoms. 1. In cases of absence of clinical signs and symptoms, endodontic treatment will be completed. 2. In cases where patient returns with presence of clinical signs and symptoms, dressing will be removed, and canals will be irrigated with sodium hypochlorite followed by saline. After drying the canals, in group A, AVG will be placed in the canals and tooth restored temporarily while in group B, cotton pellet will be placed in the canals and tooth restored temporarily. The patients will be recalled after two weeks. 3. If a patient reports with acute symptomsin either of the groups, the protocols to manage acute infection will be followed.
次要结局
未报告次要终点