The Effects of COVID-19 Infection on Respiratory Muscle Strength and Core Stabilization

Completed

• Conditions: COVID-19; Pandemic, COVID-19; Corona Virus Infection

• Registration Number: NCT05461391
• Lead Sponsor: Yeditepe University

Brief Summary

World Health Organization (WHO) Novel-19 Corrosion Disease (COVID) in 2019 without being used by a pathway caused by the SARS-CoV-2 virus. After the acute period in COVID-19 patients, muscle weakness may continue in breathing, weakness, and training. The effects on core stabilization, pulmonary functions, respiratory muscle strength, physical activity scores and quality of life in healthy adults who do not have COVID-19 who do regular exercise may be higher than in healthy adults who do regular exercise with COVID-19.

Detailed Description

The type of our study was planned as Case-Control. 50 exercises will be included in our study. The first COVID-19 (n= 25) is healthy, and the second group will come from the successful group without COVID-19 (n=25). Between February and April, a student will accept participating in the clinic at Bezmialem Foundation University. After being informed about it, the attached form will be signed. In addition, participants will be asked to fill in our attached document, including demographic and clinical studies, in a face-to-face interview. All body exercises, breathing muscle test, six-minute walking test, McGill core endurance test, short-form test, and quality of life test were planned in our two groups. The results of these tests will be evaluated by testing and checking.

Study Timeline

• Study First Submitted: 2022-02-12
• Study Start: 2022-03-15
• Primary Completion: 2022-05-15
• Study Completion: 2022-06-30
• Study First Submitted QC: 2022-07-14
• Study First Posted: 2022-07-18
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-17
• Last Update Posted: 2023-08-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. To be between the ages of 18-50,
2. Volunteering to participate in the research,
3. Those who have done aerobic exercise at least three days a week in the last three months

Exclusion Criteria

1. Neurological deficits in the upper or lower extremities,
2. Fractures or orthopedic problems in the upper or lower extremities,
3. Cardiovascular diseases that prevent rehabilitation,
4. Systematic rheumatic disease (rheumatoid arthritis, ankylosing spondylitis),
5. History of surgery in the last three months,
6. Patients with spine problems,
7. Smokers,
8. Patients with chronic respiratory problems.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pulmonary Function Test	8 weeks	Medical International Research Spirodoc® Spiro spirometry will evaluate the respiratory functions of Italian brand volunteers. Lung function tests can determine both expected values and deviations of lung volumes. Spirometry has been used for over 150 years. Spirometry tests objectively evaluate both inspiratory and expiratory patients. The test will be repeated three times, and the best values will be recorded before and after the interventions.
Respiratory Muscle Strength	8 weeks	Mikro Medical Micro RPM is aimed to measure Maximal Inspiratory Pressure (MIP) and Maximal Expiratory Pressure (MEP) values. During the application, maximum effort is requested, and the patient will be shown the test beforehand. During the measurement of MIP and MEP, it is closed with a nose clip, and after a deep breath, volunteers will be asked to give a maximum exhale for 1 to 3 seconds.
Six Minute Walk Test (6MWT)	8 weeks	The 6MWT is a test that patients most commonly use, is valid, inexpensive, popular, easy to tolerate, easy to use, has minimal technological resources, and shows daily activity compared to other walking tests. They will be asked to walk at the same speed for 6 minutes, but not to run, on a 30-meter straight corridor. The volunteers' distance walked in 6 minutes will be calculated and evaluated.
McGill Core Endurance Test	8 weeks	McGill Core Endurance Test consists of 4 different test positions. It assesses the core endurance of volunteers.

Secondary Outcome Measures

Name	Time	Method
International Physical Activity Questionnaire - Short Form (IPAQ-SF)	8 weeks	The IPAQ is the most widely used physical activity questionnaire to describe young and middle-aged adults (15-69 years) participation in physical activity. IPAQ-SF (short form) provides individual results for walking, moderate-intensity, and vigorous-intensity activity scores. The three physical activities' duration (in minutes) and frequency (in days) give the total score. Scores used for Mean Metabolic Task Equivalent (MET) values, total physical activity MET-minutes/week = Total walking + Moderate + Vigorous MET minutes/week scores. Survey questions will be asked to the participants face to face by the researcher, and the answers will be recorded.
Quality of Life Scale (SF36)	8 weeks	It was planned to evaluate the quality of life of the volunteers with SF36.
Dyspnea Scale	8 weeks	The Modified Medical Research Council Scale (MMRC) is used to investigate the severity of dyspnea during activity in people with and without the disease. The MMRC is a five-item scale based on various activities that cause shortness of breath. Volunteers easily mark the activity level that causes dyspnea on the scale. The story of dyspnea in patients is graded from the "0" point, and the "0" point indicates the absence of dyspnea. The survey questions will be asked to the participants face to face by the researcher, and the answers will be recorded.

Trial Locations

Locations (1)

Bezmialem Vakif University Dragos Hospital; 🇹🇷 Istanbul, Maltepe, Turkey