Are pulmonary function test suitable to support the choice for a dental brace treatment in patients with sleep apnea?
Completed
- Conditions
- Obstructive Sleep Apnea Mandibular Advancement Thearpy
- Registration Number
- NL-OMON22296
- Lead Sponsor
- Medisch Spectrum TwentePostbus 50 000 7500 KA Enschede053 487 20 00
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 25
Inclusion Criteria
Obstructive Sleep Apnea (OSAS) patients with an age of ≥ 18 years.
Apnoea-hypopnoea index (AHI) ≥ 15
Exclusion Criteria
Inability to read and/or understand the Dutch language.
Having a control polygraph after an initial polysomnography
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The diagnostic accuracy, expressed as sensitivity, specificity, negative predictive value and positive predictive value, for the different measurement parameters. The parameters of the different measurements are: <br /><br>- Spirometry: absolute difference between the ratios of the expiratory flow rate at 50% of vital capacity to the inspiratory flow rate at 50% of vital capacity (MEF50:MIF50) obtained by the MAD in maximal retracted and maximal protrusive position.<br /><br>- FOT: absolute difference between the mid-frequency resistances (R20) obtained by the MAD in maximal retracted and maximal protrusive position.<br /><br>- NEP: absolute difference in flow drops (ΔV ̇) as a percentage of the peak flows (%Vpeak) obtained by the MAD in maximal retracted and maximal protrusive position.<br>
- Secondary Outcome Measures
Name Time Method