Development of a Personalized Discussion Prioritization Tool for Older Adults Considering Adjuvant Chemotherapy for Breast Cancer

Not Applicable

Completed

• Conditions: Breast Cancer
• Interventions: Other: Experimental

• Registration Number: NCT05073432
• Lead Sponsor: University of Rochester

Brief Summary

The investigators have developed a Discussion Prioritization Tool (DPT) for older adults consider adjuvant chemotherapy that utilizes Conjoint Analysis (CA) methodology and the objective of the current study is to assess usability of this DPT in the target population, older adults with breast cancer and to adapt the tool to optimize usability for the target population.

Detailed Description

Given the complexity of adjuvant chemotherapy decision making for older adults with breast cancer, enhancing support and promoting treatment discussions in the context of patient's goals and preferences is an important need. With this need in mind, the investigators have completed interviews with patients with cancer patients who are considering adjuvant therapy. As a result of these interviews, the investigators have developed a common list of attributes (variables found to be important in decision making) that were used to create the Discussion Prioritization Tool (DPT) using Conjoint Analysis (CA) methodology. CA which is a method that can assess the relative importance that patients place on different aspects of care by asking patients to make a series of trade-offs between competing options. The purpose of this study is to assess the usability of a Discussion Prioritization Tool, administered through a tablet, laptop, or computer, for its ability to aid in treatment decision-making. The investigators would like to gather feedback from individuals to improve and adapt the communication tool.

Study Timeline

• Study Start: 2021-07-28
• Study First Submitted: 2021-09-28
• Study First Submitted QC: 2021-09-28
• Study First Posted: 2021-10-11
• Primary Completion: 2023-03-15
• Study Completion: 2023-03-15
• Results First Submitted: 2024-03-13
• Results First Submitted QC: 2024-10-09
• Results First Posted: 2024-10-15
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-22
• Last Update Posted: 2025-04-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Age ≥65
• Diagnosis of stage I-III BC
• Being considered for adjuvant chemotherapy
• Able to speak and read English
• Able to participate in study procedures.

Exclusion Criteria

• Lacking medical decision-making capacity as determined by their oncologist
• Evidence of metastatic disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Experimental	Experimental	Electronic completion of Geriatric Assessment and Conjoint Analysis with result output.

Primary Outcome Measures

Name	Time	Method
Functional Assessment of the Discussion Prioritization Tool (DPT)	2 Months	System Usability Scale (SUS) (score on a 10-item scale, with a total score ranging from 0-100; a higher score corresponds to greater usability). We will deem the tool usable if our mean SUS score among the 10 patients enrolled is \>68.

Trial Locations

Locations (1)

University of Rochester; 🇺🇸 Rochester, New York, United States