Analysis of risk factors and prediction model of disease progression in people with impaired glucose tolerance (IGT)
- Conditions
- Impaired glucose tolerance
- Registration Number
- ITMCTR2100004224
- Lead Sponsor
- The Affiliated Hospital of Changchun University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. People with impaired glucose tolerance;
1) Aged 18 to 75 years;
2) Meet the diagnostic criteria of Western medicine for IGT;
4) Informed consent has been signed.
2. Healthy people:
1)Aged 18 to 70 years;
2) According to the diagnostic criteria of healthy people, the constitution of traditional Chinese medicine was judged as peaceful constitution;
3) There was no history of chronic diseases, such as diabetes and its pre status, hypertension, hyperlipidemia, hyperuricemia, overweight / obesity, coronary heart disease, etc;
4) Physical examination and blood glucose test data were normal;
5) Informed consent has been signed.
1) People who have used hypoglycemic drugs continuously in recent 3 months;
2) Patients who have been diagnosed with type 1 diabetes, type 2 diabetes, gestational diabetes, secondary diabetes and other special types of diabetes;
3) Patients with severe other diseases or mental disorders;
4) Due to the poor compliance of the protocol, the researcher considered that it was not suitable to participate in the study;
5) Pregnant or lactating women and those who have recently had family planning;
6) Patients with impaired liver and kidney function (ALT and AST are twice higher than the upper limit of normal value, and serum creatinine is abnormal).
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of diabetes mellitus;
- Secondary Outcome Measures
Name Time Method blood pressure;Fasting and 2-hour postprandial blood glucose;Constitution of traditional Chinese Medicine;liver function;glycosylated hemoglobin;Waist hip ratio;renal function;Insulin resistance index(HOMA-IR);Fasting insulin;the routine urine test;Stool routine;routine blood test;Syndrome of traditional Chinese Medicine;Blood?lipid;Body mass index;