Effects of alpha-lipoic acid on patients undergoing hemodialysis
Phase 2
Completed
- Conditions
- Patient undergoing hemodialysis.Chronic kidney disease, stage 5N18.5
- Registration Number
- IRCT20160206026390N12
- Lead Sponsor
- Shahrekord University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
Patients (20-80 yr.) with a history of hemodialysis treatment for a minimum of six months
Willing to participate in the trial
Exclusion Criteria
-Any recent significant changes in patients' lifestyle behaviors (diet, physical activity, stress)
-History of consuming any antioxidant or anti-inflammatory dietary supplements less than one month before study enrollment
-Possible kidney transplantation
-History of alcohol consumption
-History of cigarette smoking
-Allergies or intolerance to alpha-lipoic acid
-History of cancer
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total Antioxidant Capacity. Timepoint: Before and after study. Method of measurement: Laboratory kits.;Tumor necrosis factor- alpha. Timepoint: Before and after study. Method of measurement: Laboratory kits.;Erythroblast Sedimentation Rate. Timepoint: Before and after study. Method of measurement: Laboratory kits.;Interleukin - 6. Timepoint: Before and after study. Method of measurement: Laboratory kits.;C-reactive Protein. Timepoint: Before and after study. Method of measurement: Laboratory kits.;Irisin. Timepoint: Before and after study. Method of measurement: Laboratory kits.
- Secondary Outcome Measures
Name Time Method Weight. Timepoint: Befor and after Study. Method of measurement: Sensitive Balance.