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Clinical Trials/NCT03970421
NCT03970421
Unknown
Not Applicable

Demographic and Clinical Data Associated to Head Injury Severity on Adults Patients (Older Than 16yo), and Follow up for 90 Days to Check the Development of Associated Complications, Deciding the Optimal Observation Lapse at ED

Hospital El Escorial1 site in 1 country300 target enrollmentJune 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Head Injury Other
Sponsor
Hospital El Escorial
Enrollment
300
Locations
1
Primary Endpoint
Development of haemorragical complications during observation time
Last Updated
6 years ago

Overview

Brief Summary

We know precisely which patients and when they should have an imaging test to evaluate a Head Injury (HI). But in those patients on anticoagulant and / or antiaggregant treatment we do not know the exact incidence of early and late hemorrhagic lesions, and there is no specific recommendation on how long they should remain under observation in the emergency department if no initial lesions are evident. Our goal is to try to answer these two questions.

Detailed Description

MATERIAL: Prospective study of patients treated of HI in the Emergency Department (ED) and to whom an image test is performed (cranial CT scan). Collection of demographic, clinical, analytical, image tests, and observation time in the emergency department (from admission to medical discharge) METHODS: Separation of subjects included in the study in 4 cohorts: patients without anticoagulant and / or antiaggregant treatment; patients with antiplatelet therapy (ASA and / or clopidogrel); patients with anticoagulant treatment with acenocoumarol and INR \<2; and patients on anticoagulant therapy with acenocoumarol and INR\> = 2 or patients on treatment with direct thrombin inhibitors (dabigatran), or inhibitors of factor Xa (rivaroxaban, apixaban, edoxaban) or patients on treatment with low molecular weight heparins (LMWH) ) Follow-up through analysis of clinical history and telephone interview at 2, 7, 15, 30, 60 and 90 days. Statistical analysis of the results.

Registry
clinicaltrials.gov
Start Date
June 2019
End Date
March 2020
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • HI attended at ED
  • Head CT performed as recommended by clinical guides
  • Contact data available (phone number)

Exclusion Criteria

  • Patients not able for follow up (foreigners or tourists or whatsoever whom are not going to stay on the country for at least 3 months)

Outcomes

Primary Outcomes

Development of haemorragical complications during observation time

Time Frame: 90 days

Finding of an haemorragical injury associated with the head injury during follow up

Severity factors associated to head injury

Time Frame: 24 hours

Demographical, clinical, analitical, and neuroimaging data associated to severity of HI

Study Sites (1)

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